Making the DEA's Most Hated Decongestant

Duration: 23:07

Go to https://ground.news/Labcoatz to see how any news story is being framed by news outlets around the world and across the political spectrum. Use my link to get 50% off unlimited access with the Vantage Subscription. And check out @chemdelic for more awesome chemistry content, including his unique approach to getting nitroethane: https://www.youtube.com/watch?v=G-poNCUViqY Want to support LabCoatz directly? Of course you do! Feel free to join my Patreon here, or simply donate using the PayPal link: https://www.patreon.com/c/LabCoatz https://www.paypal.com/paypalme/labcoatz WARNING: while completely legal and VERY SAFE when used as directed, you should NOT take propylhexedrine recreationally. Its effects are fairly weak compared to related chemicals, and it comes with a variety of unpleasant side effects (high blood pressure, stress, nausea/vomiting, and even psychosis). The chemicals used in this synthesis also pose their own unique risks...many are toxic (especially mercury and formaldehyde), and the rest are either flammable or corrosive. Given the exceptionally low yield, questionable purity, high cost, and near-impossibility of obtaining the necessary reagents, I cannot recommend trying this at home. 0:00 Intro 1:00 Introducing: propylhexedrine 1:43 First attempt 4:11 Sponsored segment 6:15 New pathway, new ingredients 7:05 The Henry reaction 8:59 Problems arise 9:48 Nitropropene reduction 11:39 Norpropylhexedrine workup 13:02 Freebasing: did the reaction work?? 14:05 Reductive amination to propylhexedrine 17:02 Propylhexedrine? 19:03 Final yield 19:57 Testing the product